Pharmacological Treatment of Methamphetamine Amphetamine Dependence: A Systematic Review

Pharmacological Treatment of Methamphetamine Amphetamine Dependence: A Systematic Review

Amphetamine dependence

Talk with your doctor if you’re pregnant or planning to become pregnant. This medication should be used during pregnancy only if the benefit justifies the potential risk. Also, tests may be done to check for heart problems, breathing problems, and oxygen levels. And medications may be needed for heart problems or seizures if they occur.

  • For more information on the possible side effects of Adderall, or tips on how to deal with a troubling side effect, talk with your doctor or pharmacist.
  • There haven’t been enough studies done in humans to be sure about how Adderall might affect a fetus if taken during pregnancy.
  • Before taking Adderall, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take.
  • For abstinence, urine drug screens (UDS) were used 41 times (80%) and analysed or defined in 16 different ways.
  • However, none of these are proven to prevent amphetamine use in everyone.

Research data policy

If the diagnosis is unclear, urine tests may be done, but the test may not detect methamphetamine and methylphenidate (a stimulant drug related to amphetamines). People who habitually use amphetamines rapidly develop tolerance as part of dependence. The amount ultimately used may be more than several times the original dose. Most people using very high doses over several days or weeks become confused and psychotic because amphetamines can cause severe anxiety, paranoia, and a distorted sense of reality. Topiramate was assessed in two studies reviewed here 32, 55, Amphetamine Addiction demonstrating reduced use and addiction severity compared with placebo.

The Resilience on Amphetamine Relapse Youth (RARY) Scale

Norepinephrine is a neurotransmitter, a chemical that sends messages between cells. Both Adderall and modafinil can cause physical and psychological dependence leading to misuse (also called abuse). However, dependence appears to be more common with Adderall than modafinil. Modafinil is approved to treat narcolepsy, shift-work sleep disorder, and sleep apnea. This means that it’s not FDA-approved for this purpose, but there is some scientific evidence that it might help.

Results of Individual Studies

Amphetamine dependence

The study’s findings might be valuable for future research and clinical assessment. Therefore, the final version of the Resilience on Amphetamine Relapse Youth (RARY) Scale comprised 41 items with six factors named as the following. The nature of the questions is one-way positive, with each question requiring the respondent to choose only one answer. The tool is scored based on the responses to the individual items, with each item contributing to the Alcoholics Anonymous relevant factors. There is no single total score for the entire tool, as the focus is on assessing the six separate factors rather than an overall composite score.

  • Treatment focuses on the person who is living with the addiction.
  • Drinking alcohol while taking Adderall can make people feel less drunk than they really are.
  • Misusing amphetamines, or taking them in a different way than a doctor prescribes, can lead to amphetamine addiction.
  • The limitation of this study is an imbalanced gender distribution.

Adderall and methylphenidate are both commonly used to treat ADHD. Strattera, on the other hand, is typically used for those who don’t want to take a stimulant medication or who can’t take stimulants due to side effects or other reasons. Adderall, a stimulant, is considered a first-choice treatment for ADHD. Stimulants are the best studied and most effective treatments for ADHD. Strattera also works in the brain but doesn’t have stimulant effects. It works as a selective norepinephrine reuptake inhibitor and increases the amount of norepinephrine in parts of the brain.

Amphetamine dependence

This perspective is consistent with Meschke & Patterson, who argued that adolescent substance uses stems from a combination of factors rather than being solely determined by risk factors alone19. They emphasized that even when adolescents face risk factors for substance use, the presence of protective factors can counteract these influences. By fostering protective factors like social support, mental health care, and emotional coping skills, resilience can help mitigate the impact of risk factors and enhance long-term well-being. Furthermore, adolescents who are able to effectively manage situations that might lead to substance use are more likely to adapt to stress without resorting to substances.

Amphetamine dependence

Your mental health is affected

Prescription drug monitoring programs track the prescribing and dispensing of controlled medications to people. However, these programs have been more successful in some states than others. These changes to the brain mean that a person may always be at risk of using a substance again, even if they have not used it for a long time. An individual’s brain chemistry changes during regular misuse of a substance or activity.

Amphetamine dependence

Many amphetamines are Schedule II stimulants, which means they have a high potential for abuse and are legally available only through a prescription. When used for medical purposes, the doses are much lower than those typical among abusers of the drugs. Studies examining the efficacy of pharmacotherapy alone versus combined medication and psychosocial counselling are required to better understand the role each treatment modality may have. Provision of client-centred care requires future work to address the need to better understand concepts of treatment matching or stepped care. Further, treatments may differ by dose and frequency (intensity) of use. Irrespective of the promise of pharmacotherapy, effective treatment of substance use disorders requires comprehensive biopsychosocial intervention.

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